In my estimation this is the only problem that really matters. It’s all encompassing, and it’s practically insurmountable. Commenter Don sums it up succinctly:

These monsters have done things that can never be undone and the total consequences will never be known.

You’re right, Don, but I will go one further: It’s not just depleted uranium or agent orange or Nigerian oil spills that nobody in the developed world ever hears about or the other explicit (albeit hidden) costs of imperialism. The stockpiles of nuclear and other weapons of mass- and indiscriminate destruction; the use of such weapons including depleted uranium, etc., the de facto strip-mining of the Earth’s resources — these are globally existential threats to peace and humanity.

Most people are probably aware of nuclear stockpiles, that cold war remnant with which nobody knows exactly what to do. But there is a reason you’ve probably never heard about the Nigerian oil spills or countless other exploitations of a people and an ecosystem; a reason you’ve probably never heard much about depleted uranium or white phosphorous. They do not want you to know.

And so you don’t.

These aren’t naturally occurring, rather the people at large were manipulated in to sowing the seeds (which will probably one day become the source of our collective destruction), all of these threats had their genesis in the ruling classes’ interests, as a means towards achieving some outcome they desired, consequences be damned.

The issue is this: There are simply no means available to deal with or to mitigate the loss or potential for loss attributable to  many of the problems that the State has created.  Even if we could abolish the state tomorrow, these problems they created which nobody wanted in the first place, remain.